WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_SCGGAAGY_V$ELK1_02       ID:DB_ID:2413
C=1176; O=22; E=3.16; R=6.96; rawP=7.71e-13; adjP=2.34e-10
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115207 NA GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 2976 ENSG00000115207
2  ENSG00000126746 NA ZNF384 zinc finger protein 384 171017 ENSG00000126746
3  ENSG00000063244 NA U2AF2 U2 small nuclear RNA auxiliary factor 2 11338 ENSG00000063244
4  ENSG00000105726 NA ATP13A1 ATPase type 13A1 57130 ENSG00000105726
5  ENSG00000100083 NA GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 26088 ENSG00000100083
6  ENSG00000087157 NA PGS1 phosphatidylglycerophosphate synthase 1 9489 ENSG00000087157
7  ENSG00000213923 NA CSNK1E casein kinase 1, epsilon 1454 ENSG00000213923
8  ENSG00000141140 NA MYO19 myosin XIX 80179 ENSG00000141140
9  ENSG00000076201 NA PTPN23 protein tyrosine phosphatase, non-receptor type 23 25930 ENSG00000076201
10  ENSG00000131748 NA STARD3 StAR-related lipid transfer (START) domain containing 3 10948 ENSG00000131748
11  ENSG00000100813 NA ACIN1 apoptotic chromatin condensation inducer 1 22985 ENSG00000100813
12  ENSG00000163463 NA KRTCAP2 keratinocyte associated protein 2 200185 ENSG00000163463
13  ENSG00000088038 NA CNOT3 CCR4-NOT transcription complex, subunit 3 4849 ENSG00000088038
14  ENSG00000101199 NA ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 55738 ENSG00000101199
15  ENSG00000182325 NA FBXL6 F-box and leucine-rich repeat protein 6 26233 ENSG00000182325
16  ENSG00000161847 NA RAVER1 ribonucleoprotein, PTB-binding 1 125950 ENSG00000161847
17  ENSG00000104859 NA CLASRP CLK4-associating serine/arginine rich protein 11129 ENSG00000104859
18  ENSG00000099917 NA MED15 mediator complex subunit 15 51586 ENSG00000099917
19  ENSG00000120685 NA PROSER1 proline and serine rich 1 80209 ENSG00000120685
20  ENSG00000100023 NA PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 23759 ENSG00000100023
21  ENSG00000066056 NA TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 7075 ENSG00000066056
22  ENSG00000242028 NA C15orf63 chromosome 15 open reading frame 63 25764 ENSG00000242028


Database:Transcription Target       Name:hsa_RCGCANGCGY_V$NRF1_Q6       ID:DB_ID:2441
C=894; O=17; E=2.40; R=7.07; rawP=3.12e-10; adjP=4.74e-08
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115207 NA GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 2976 ENSG00000115207
2  ENSG00000063244 NA U2AF2 U2 small nuclear RNA auxiliary factor 2 11338 ENSG00000063244
3  ENSG00000214078 NA CPNE1 copine I 8904 ENSG00000214078
4  ENSG00000168066 NA SF1 splicing factor 1 7536 ENSG00000168066
5  ENSG00000177303 NA CASKIN2 CASK interacting protein 2 57513 ENSG00000177303
6  ENSG00000109118 NA PHF12 PHD finger protein 12 57649 ENSG00000109118
7  ENSG00000100813 NA ACIN1 apoptotic chromatin condensation inducer 1 22985 ENSG00000100813
8  ENSG00000185324 NA CDK10 cyclin-dependent kinase 10 8558 ENSG00000185324
9  ENSG00000130726 NA TRIM28 tripartite motif containing 28 10155 ENSG00000130726
10  ENSG00000181222 NA POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 5430 ENSG00000181222
11  ENSG00000079277 NA MKNK1 MAP kinase interacting serine/threonine kinase 1 8569 ENSG00000079277
12  ENSG00000161847 NA RAVER1 ribonucleoprotein, PTB-binding 1 125950 ENSG00000161847
13  ENSG00000160633 NA SAFB scaffold attachment factor B 6294 ENSG00000160633
14  ENSG00000168488 NA ATXN2L ataxin 2-like 11273 ENSG00000168488
15  ENSG00000126012 NA KDM5C lysine (K)-specific demethylase 5C 8242 ENSG00000126012
16  ENSG00000213983 NA AP1G2 adaptor-related protein complex 1, gamma 2 subunit 8906 ENSG00000213983
17  ENSG00000136699 NA SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) 55627 ENSG00000136699


Database:Transcription Target       Name:hsa_GGGCGGR_V$SP1_Q6       ID:DB_ID:2452
C=2891; O=26; E=7.78; R=3.34; rawP=4.13e-08; adjP=4.19e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000126746 NA ZNF384 zinc finger protein 384 171017 ENSG00000126746
2  ENSG00000214078 NA CPNE1 copine I 8904 ENSG00000214078
3  ENSG00000156983 NA BRPF1 bromodomain and PHD finger containing, 1 7862 ENSG00000156983
4  ENSG00000100083 NA GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 26088 ENSG00000100083
5  ENSG00000156304 NA SCAF4 SR-related CTD-associated factor 4 57466 ENSG00000156304
6  ENSG00000158545 NA ZC3H18 zinc finger CCCH-type containing 18 124245 ENSG00000158545
7  ENSG00000141140 NA MYO19 myosin XIX 80179 ENSG00000141140
8  ENSG00000076201 NA PTPN23 protein tyrosine phosphatase, non-receptor type 23 25930 ENSG00000076201
9  ENSG00000115275 NA MOGS mannosyl-oligosaccharide glucosidase 7841 ENSG00000115275
10  ENSG00000131748 NA STARD3 StAR-related lipid transfer (START) domain containing 3 10948 ENSG00000131748
11  ENSG00000177303 NA CASKIN2 CASK interacting protein 2 57513 ENSG00000177303
12  ENSG00000109118 NA PHF12 PHD finger protein 12 57649 ENSG00000109118
13  ENSG00000125447 NA GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 23163 ENSG00000125447
14  ENSG00000163463 NA KRTCAP2 keratinocyte associated protein 2 200185 ENSG00000163463
15  ENSG00000130726 NA TRIM28 tripartite motif containing 28 10155 ENSG00000130726
16  ENSG00000181222 NA POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 5430 ENSG00000181222
17  ENSG00000088038 NA CNOT3 CCR4-NOT transcription complex, subunit 3 4849 ENSG00000088038
18  ENSG00000161904 NA LEMD2 LEM domain containing 2 221496 ENSG00000161904
19  ENSG00000161847 NA RAVER1 ribonucleoprotein, PTB-binding 1 125950 ENSG00000161847
20  ENSG00000160633 NA SAFB scaffold attachment factor B 6294 ENSG00000160633
21  ENSG00000168488 NA ATXN2L ataxin 2-like 11273 ENSG00000168488
22  ENSG00000088247 NA KHSRP KH-type splicing regulatory protein 8570 ENSG00000088247
23  ENSG00000213983 NA AP1G2 adaptor-related protein complex 1, gamma 2 subunit 8906 ENSG00000213983
24  ENSG00000077454 NA LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 4034 ENSG00000077454
25  ENSG00000242028 NA C15orf63 chromosome 15 open reading frame 63 25764 ENSG00000242028
26  ENSG00000104960 NA PTOV1 prostate tumor overexpressed 1 53635 ENSG00000104960


Database:Transcription Target       Name:hsa_GCCATNTTG_V$YY1_Q6       ID:DB_ID:2459
C=419; O=10; E=1.13; R=8.87; rawP=2.20e-07; adjP=1.67e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000063244 NA U2AF2 U2 small nuclear RNA auxiliary factor 2 11338 ENSG00000063244
2  ENSG00000214078 NA CPNE1 copine I 8904 ENSG00000214078
3  ENSG00000146067 NA FAM193B family with sequence similarity 193, member B 54540 ENSG00000146067
4  ENSG00000160633 NA SAFB scaffold attachment factor B 6294 ENSG00000160633
5  ENSG00000079313 NA REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) 57455 ENSG00000079313
6  ENSG00000198026 NA ZNF335 zinc finger protein 335 63925 ENSG00000198026
7  ENSG00000109118 NA PHF12 PHD finger protein 12 57649 ENSG00000109118
8  ENSG00000181222 NA POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 5430 ENSG00000181222
9  ENSG00000088038 NA CNOT3 CCR4-NOT transcription complex, subunit 3 4849 ENSG00000088038
10  ENSG00000108349 NA CASC3 cancer susceptibility candidate 3 22794 ENSG00000108349


Database:Transcription Target       Name:hsa_V$NFMUE1_Q6       ID:DB_ID:2191
C=239; O=8; E=0.64; R=12.44; rawP=3.00e-07; adjP=1.82e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000214078 NA CPNE1 copine I 8904 ENSG00000214078
2  ENSG00000105726 NA ATP13A1 ATPase type 13A1 57130 ENSG00000105726
3  ENSG00000168066 NA SF1 splicing factor 1 7536 ENSG00000168066
4  ENSG00000079313 NA REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) 57455 ENSG00000079313
5  ENSG00000126012 NA KDM5C lysine (K)-specific demethylase 5C 8242 ENSG00000126012
6  ENSG00000220205 NA VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 6844 ENSG00000220205 ENSG00000263620
7  ENSG00000161021 NA MAML1 mastermind-like 1 (Drosophila) 9794 ENSG00000161021
8  ENSG00000088038 NA CNOT3 CCR4-NOT transcription complex, subunit 3 4849 ENSG00000088038


Database:Transcription Target       Name:hsa_GGAANCGGAANY_UNKNOWN       ID:DB_ID:2258
C=106; O=6; E=0.29; R=21.04; rawP=4.55e-07; adjP=2.31e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000126746 NA ZNF384 zinc finger protein 384 171017 ENSG00000126746
2  ENSG00000063244 NA U2AF2 U2 small nuclear RNA auxiliary factor 2 11338 ENSG00000063244
3  ENSG00000163482 NA STK36 serine/threonine kinase 36 27148 ENSG00000163482
4  ENSG00000104859 NA CLASRP CLK4-associating serine/arginine rich protein 11129 ENSG00000104859
5  ENSG00000100083 NA GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 26088 ENSG00000100083
6  ENSG00000087157 NA PGS1 phosphatidylglycerophosphate synthase 1 9489 ENSG00000087157


Database:Transcription Target       Name:hsa_CAGGTA_V$AREB6_01       ID:DB_ID:2404
C=780; O=12; E=2.10; R=5.72; rawP=1.39e-06; adjP=6.04e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000156983 NA BRPF1 bromodomain and PHD finger containing, 1 7862 ENSG00000156983
2  ENSG00000168066 NA SF1 splicing factor 1 7536 ENSG00000168066
3  ENSG00000146067 NA FAM193B family with sequence similarity 193, member B 54540 ENSG00000146067
4  ENSG00000079432 NA CIC capicua homolog (Drosophila) 23152 ENSG00000079432
5  ENSG00000073169 NA SELO selenoprotein O 83642 ENSG00000073169
6  ENSG00000099904 NA ZDHHC8 zinc finger, DHHC-type containing 8 29801 ENSG00000099904
7  ENSG00000158545 NA ZC3H18 zinc finger CCCH-type containing 18 124245 ENSG00000158545
8  ENSG00000181220 NA ZNF746 zinc finger protein 746 155061 ENSG00000181220
9  ENSG00000109118 NA PHF12 PHD finger protein 12 57649 ENSG00000109118
10  ENSG00000142102 NA ATHL1 ATH1, acid trehalase-like 1 (yeast) 80162 ENSG00000142102
11  ENSG00000125386 NA FAM193A family with sequence similarity 193, member A 8603 ENSG00000125386
12  ENSG00000156860 NA FBRS fibrosin 64319 ENSG00000156860


Database:Transcription Target       Name:hsa_V$PAX4_01       ID:DB_ID:2064
C=261; O=7; E=0.70; R=9.97; rawP=7.30e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000161904 NA LEMD2 LEM domain containing 2 221496 ENSG00000161904
2  ENSG00000115207 NA GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 2976 ENSG00000115207
3  ENSG00000214078 NA CPNE1 copine I 8904 ENSG00000214078
4  ENSG00000109118 NA PHF12 PHD finger protein 12 57649 ENSG00000109118
5  ENSG00000161021 NA MAML1 mastermind-like 1 (Drosophila) 9794 ENSG00000161021
6  ENSG00000079432 NA CIC capicua homolog (Drosophila) 23152 ENSG00000079432
7  ENSG00000076201 NA PTPN23 protein tyrosine phosphatase, non-receptor type 23 25930 ENSG00000076201


Database:Transcription Target       Name:hsa_GGGAGGRR_V$MAZ_Q6       ID:DB_ID:2430
C=2250; O=18; E=6.05; R=2.97; rawP=3.24e-05; adjP=0.0011
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000126746 NA ZNF384 zinc finger protein 384 171017 ENSG00000126746
2  ENSG00000168066 NA SF1 splicing factor 1 7536 ENSG00000168066
3  ENSG00000218891 NA ZNF579 zinc finger protein 579 163033 ENSG00000218891
4  ENSG00000079432 NA CIC capicua homolog (Drosophila) 23152 ENSG00000079432
5  ENSG00000213923 NA CSNK1E casein kinase 1, epsilon 1454 ENSG00000213923
6  ENSG00000141140 NA MYO19 myosin XIX 80179 ENSG00000141140
7  ENSG00000177303 NA CASKIN2 CASK interacting protein 2 57513 ENSG00000177303
8  ENSG00000109118 NA PHF12 PHD finger protein 12 57649 ENSG00000109118
9  ENSG00000163463 NA KRTCAP2 keratinocyte associated protein 2 200185 ENSG00000163463
10  ENSG00000039523 NA FAM65A family with sequence similarity 65, member A 79567 ENSG00000039523
11  ENSG00000181222 NA POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 5430 ENSG00000181222
12  ENSG00000088038 NA CNOT3 CCR4-NOT transcription complex, subunit 3 4849 ENSG00000088038
13  ENSG00000156860 NA FBRS fibrosin 64319 ENSG00000156860
14  ENSG00000160741 NA CRTC2 CREB regulated transcription coactivator 2 200186 ENSG00000160741
15  ENSG00000168488 NA ATXN2L ataxin 2-like 11273 ENSG00000168488
16  ENSG00000088247 NA KHSRP KH-type splicing regulatory protein 8570 ENSG00000088247
17  ENSG00000066056 NA TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 7075 ENSG00000066056
18  ENSG00000077454 NA LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 4034 ENSG00000077454


Database:Transcription Target       Name:hsa_V$CACBINDINGPROTEIN_Q6       ID:DB_ID:2219
C=238; O=6; E=0.64; R=9.37; rawP=4.74e-05; adjP=0.0013
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000177303 NA CASKIN2 CASK interacting protein 2 57513 ENSG00000177303
2  ENSG00000109118 NA PHF12 PHD finger protein 12 57649 ENSG00000109118
3  ENSG00000100813 NA ACIN1 apoptotic chromatin condensation inducer 1 22985 ENSG00000100813
4  ENSG00000163463 NA KRTCAP2 keratinocyte associated protein 2 200185 ENSG00000163463
5  ENSG00000218891 NA ZNF579 zinc finger protein 579 163033 ENSG00000218891
6  ENSG00000156860 NA FBRS fibrosin 64319 ENSG00000156860




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).